POSTER PRESENTATION
APDW 2014
Bali, 22-25 Nopember 2014
Effect
of Ramadhan Fasting to Dyspeptic Symptoms on Outpatient based on Dysepsia Symptoms Severity Index
(DSSI) Scores
Suzanna Ndraha, Eddy Chandra
Faculty of Medicine, University of
Krida Wacana, Jakarta
Background: One of the risk factor for dyspepsia is fasting, include Ramadhan
fasting. Proton pump inhibitors (PPIs) are
drugs commonly given to patients with dyspepsia
mechanism controlling gastric acid secretion.
The aim of this study is to find the effect of Ramadan fasting and omeprazole
treatment on dyspeptic complaints
based on Dyspepsia symptoms severity index (DSSI)
score.
Method: Using analytic study design, conducted in
outpatient Koja Hospital from June 2013 until July 2013, for all patients with
dyspepsia who will be run ramadhan fasting. Subjects are divided into 2 groups,
one group was given omeprazole during fasting, while others were given a
placebo. Before and after 2 weeks of fasting DSSI scores were taken. DSSI scores assessed changes in both groups were compared using student t test.
Result and
discussion: DSSI scores on average before the
intervention (pre-test) of the two groups was not significant (p = 0.9).
In the omeprazole group obtained without worsening DSSI score from 27.7 ± 14
to 36 ± 14.8 (p = 0.001), whereas the omeprazole group obtained
scores from 27.2 ± 9.4 to 30 ± 9.9
(p = 0.08). In the group without omeprazole score
worsened by 8.3 ± 7.2 and in the omeprazole group with only 2.7 ± 5.7
(p = 0.02).
Conclusion: Deterioration
of DSSI score was significantly occurred in the group without omeprazole therapy. Omeprazole
during the month of fasting can reduce exacerbations in patients with dyspeptic
complaints.
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