Sunday, November 16, 2014

Suzanna Ndraha Poster Presentation: APDW 2014



POSTER PRESENTATION


APDW 2014
Bali, 22-25 Nopember 2014


Effect of Ramadhan Fasting to Dyspeptic Symptoms on Outpatient based on Dysepsia Symptoms Severity Index (DSSI) Scores

Suzanna Ndraha, Eddy Chandra
Faculty of Medicine, University of Krida Wacana, Jakarta


Background: One of the risk factor for dyspepsia is fasting, include Ramadhan fasting. Proton pump inhibitors (PPIs) are drugs commonly given to patients with dyspepsia mechanism controlling gastric acid secretion. The aim of this study is to find the effect of Ramadan fasting and omeprazole treatment on dyspeptic complaints based on Dyspepsia symptoms severity index (DSSI) score.
Method: Using analytic study design, conducted in outpatient Koja Hospital from June 2013 until July 2013, for all patients with dyspepsia who will be run ramadhan fasting. Subjects are divided into 2 groups, one group was given omeprazole during fasting, while others were given a placebo. Before and after 2 weeks of fasting DSSI scores were taken. DSSI scores assessed changes in both groups were compared using student t test.
Result and discussion: DSSI scores on average before the intervention (pre-test) of the two groups was not significant (p = 0.9). In the omeprazole group obtained without worsening DSSI score from 27.7 ± 14 to 36 ± 14.8 (p = 0.001), whereas the omeprazole group obtained scores from 27.2 ± 9.4 to 30 ± 9.9 (p = 0.08). In the group without omeprazole score worsened by 8.3 ± 7.2 and in the omeprazole group with only 2.7 ± 5.7 (p = 0.02).
Conclusion: Deterioration of DSSI score was significantly occurred in the group without omeprazole therapy. Omeprazole during the month of fasting can reduce exacerbations in patients with dyspeptic complaints.




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